CBD Oil for Inflammation: What Is Inflammation?

CBD oil for inflammation and chronic pain has gained popularity for its potential anti-inflammatory properties. Inflammation is a natural response by the body’s immune system to protect against injury or infection. However, chronic inflammation can lead to various health issues, including pain, swelling, and tissue damage.

While research on CBD’s effects on inflammation is ongoing, evidence suggests that CBD may have anti-inflammatory effects. CBD interacts with the body’s endocannabinoid system, which plays a role in regulates and inflammation, and it can modulate immune cell function and reduce the production of inflammatory molecules.

Some studies have shown promising results regarding the anti-inflammatory effects of CBD. For example, a 2015 study published in the Biochemical Pharmacology journal found that CBD reduced inflammation in a model of acute lung injury. Another study published in the European Journal of Pain in 2016 showed that topical CBD gel reduced joint swelling and pain in rats with arthritis.

Inflammation can be classified as either acute or chronic. Acute is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes (especially granulocytes) from the blood into the injured tissues.

Immune system imbalance

Chronic inflammation is the result of an immune system imbalance. If we can redress that, we can help cut the risk for the aforementioned long-term health problems and help ease many of the near-term low-grade ills—like skin disorders, joint pains, digestive problems, migraines, anxiety and mood swings—that many people experience as a result.

Medical researchers believe that supporting intestinal health and restoring the integrity of the gut barrier will be one of the most important goals of medicine in the 21st century.
Your gut is made of an incredibly large and complex semi-porous lining. The surface area of your gut can cover two tennis courts when stretched out flat. And its degree of permeability can change rapidly in response to a mixture of chemical conditions.
Our current lifestyle is one such chemical cocktail and it directly contributes to unhealthy gut flora:

• Antibiotics and NSAIDs

• Diets high in refined carbohydrates, sugar, and processed foods

• Diets low in fermentable fibers

• Dietary toxins like wheat, corn starch and industrial seed oils that cause leaky gut

• Chronic stress and anxiety

• Chronic infections

When the intestinal lining is repeatedly damaged it leads to a condition known as the leaky gut syndrome. This means that the damaged cells within the gut can’t do their job properly. They are unable to process and make use of the nutrients that are critical to good digestion and metabolism.
Eventually, your digestion becomes injured and absorption of nutrients is affected.
Firstly, the constant use of antibiotics is very destructive to gut flora. Recent studies have shown that antibiotic use causes an intense and rapid loss of function within the gut flora.
Bad gut flora is liable for the development of damaging gut bacteria, and these discrepancies in gut flora can result in being obese and overweight. Contracting diabetes and developing skin conditions such as eczema, psoriasis.
It is one of the likely contributors to causing depression.

 

CBD oil for anxiety .

The leaky gut syndrome is associated with many health problems.

Leaky gut can be evident in skin problems like eczema or psoriasis. It can be associated with heart failure, autoimmune conditions affecting the thyroid (Hashimoto’s) or joints (rheumatoid arthritis), mental illness, autism spectrum disorder, depression, and much more.

Leaky gut and bad gut flora are common because of the contemporary lifestyle.
If you have a leaky gut, you probably have bad gut flora and vice versa. And when your gut flora and gut barrier are weakened, you will ultimately be at high risk of inflammation.
While leaky gut syndrome and bad gut flora may be evident as digestive trouble, in many people it does not.
Instead, it shows up as dangers as varied as heart failure, depression, brain fog, eczema/psoriasis and other skin conditions, metabolic issues such as obesity and diabetes and allergies, asthma, and other autoimmune diseases.
It is becoming increasingly clear that inflammation is the root cause of many serious illnesses – including heart disease, many cancers, and Alzheimer’s disease.
We all know inflammation on the body is indicated by redness, heat, swelling, and pain. It is the basis of the body’s healing response, bringing more immune activity to a site of injury or infection.
When inflammation is felt with pain it can be a serious problem and it needs to be treated. However, when it persists or serves no purpose, it damages the body and causes illness.
Along with stress, lack of exercise, genetic bias, and exposure to toxins (like second-hand tobacco smoke), this can all add to such inflammation, which then becomes chronic.

This chronic state can lead to such conditions as fibromyalgia.

Fibromyalgia sufferers experience symptoms, including:

Insomnia or difficulty sleeping

Morning stiffness

Headaches

Numbness or tingling in the hands and feet

Menstrual irregularities and pain

Difficulty concentrating (i.e. “brain fog”)

It’s the second most common musculoskeletal ailment behind arthritis, and it affects females far more often than males (it is seven times more common in women).

It is a Debilitating Condition that Affects every Aspect of Life.

People are three to four times more likely to suffer from depression.

50% of sufferers have difficulty performing daily activities.
30–40% of people have to quit work or change jobs.
People are hospitalized once every three years on average.
The average patient uses three or four drugs daily to control symptoms.
An alternative practice of treating fibromyalgia patients is to treat gut function.
Research indicates that a majority of patients with fibromyalgia have digestive problems, with many of them having gut infections, small intestinal bacterial overgrowth (SIBO), and suffer from the leaky gut syndrome.
Therefore it follows that healing the gut is the key to long-term improvement. And how we do that is critical to how immediate health as well as our long term well being and enjoyment of life.

CBD Oil and Leaky Gut Syndrome can play a Pivotal Role

Due to these similarities between CBD and our own system, some of its incredible attributes are that it has virtually no side effects and a zero percent chance of overdose. It is a huge advantage, it works very similarly to neurochemicals called endocannabinoids that are found in our own body (and that we naturally produce).

These endocannabinoids are found to be responsible for many systems in our body, including sleep, healing, and digestion. Because the phytocannabinoids in CBD are so similar to our own endocannabinoids in the body, they act in the same way a key fits a lock
The cannabinoids fit in and activate our endocannabinoid system, stimulating healing.

CBD Oil for Inflammation: What does Research say?

Research on CBD in animal models abounds, and the cannabinoid seems to be able to interact with the immune system, reduce inflammation, and reduce pain from several conditions. Studies date back as far as 2009, but the most recent are highlighted here.

2015 review published in Bioorganic and Medicinal Chemistry discussed the anti-inflammatory properties of CBD. The reviewers found that CBD reduces inflammation through several pathways in the body, and represents an effective potential treatment for a range of conditions characterized by inflammation.

2016 study published in Clinical Hemorheology and Microcirculation investigated CBD as a treatment for early pancreatic inflammation in diabetic mice. Pancreatic inflammation can lead to diabetes due to an invasion of immune cells that destroy insulin-producing cells. The mice who received ten weeks of treatment with CBD developed diabetes later than the mice that didn’t receive the treatment. CBD-treated mice also showed a significant reduction in immune-cell activity. 

2017 study in the journal Pain examined the effects of CBD in male rats with osteoarthritis. After two weeks, acute inflammation of the joints was reduced by local CBD treatment applied to the area. The administration of CBD was also found to prevent the development of nerve damage and joint pain.

Research using animal models has shown that CBD may be able to modulate the immune system. While CBD does not have much affinity for the body’s cannabinoid receptors, it does affect other receptors and targets. According to a 2018 study published in Neurology, CBD binds to and desensitizes receptors known to mediate pain and sensory perception, inflammation, and body temperature.

While these results are promising, and most FDA-approved medication is initially tested on animals, rigorous clinical trials on humans are needed to move CBD from alternative treatment to approved drugs.

Conclusion

There is already a large body of scientific literature and anecdotal evidence that supports CBD Oil for Inflammation and it’s a potential treatment. It is critical to remember, however, that many of these existing studies have been animal studies, and that human trials are needed to understand more comprehensively how CBD works in humans.

it’s important to note that more research is needed to fully understand CBD’s anti-inflammatory effects and potential benefits for various human inflammatory conditions. The existing research is primarily preclinical or based on animal models, and human clinical trials are limited.

If you are considering using CBD oil for inflammation, it is advisable to consult with a healthcare professional. They can provide guidance based on your specific situation, help you understand potential risks and side effects, and ensure it doesn’t interfere with any other medications you may be taking.

Additionally, it’s crucial to choose a high-quality CBD product from a reputable source. Look for third-party lab testing to ensure the product’s purity and potency. Dosage and administration can vary depending on the individual and the targeted condition. Follow the product’s instructions or consult a healthcare professional for appropriate guidance.

Reference 

https://weedmaps.com/learn/cbd/cbd-oil-inflammation

https://blisshealthcoaching.com/cbd-oil-and-gut-health-can-it-improve-leaky-gut