CBD Oil for Inflammation: What Is Inflammation?
CBD oil for inflammation and chronic pain has gained popularity for its potential anti-inflammatory properties. Inflammation is a natural response by the body’s immune system to protect against injury or infection. However, chronic inflammation can lead to various health issues, including pain, swelling, and tissue damage.
While research on CBD’s effects on inflammation is ongoing, evidence suggests that CBD may have anti-inflammatory effects. CBD interacts with the body’s endocannabinoid system, which plays a role in regulates and inflammation, and it can modulate immune cell function and reduce the production of inflammatory molecules.
Some studies have shown promising results regarding the anti-inflammatory effects of CBD. For example, a 2015 study published in the Biochemical Pharmacology journal found that CBD reduced inflammation in a model of acute lung injury. Another study published in the European Journal of Pain in 2016 showed that topical CBD gel reduced joint swelling and pain in rats with arthritis.
Inflammation can be classified as either acute or chronic. Acute is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes (especially granulocytes) from the blood into the injured tissues.
Immune system imbalance
Chronic inflammation is the result of an immune system imbalance. If we can redress that, we can help cut the risk for the aforementioned long-term health problems and help ease many of the near-term low-grade ills—like skin disorders, joint pains, digestive problems, migraines, anxiety and mood swings—that many people experience as a result.
• Antibiotics and NSAIDs
• Diets high in refined carbohydrates, sugar, and processed foods
• Diets low in fermentable fibers
• Dietary toxins like wheat, corn starch and industrial seed oils that cause leaky gut
• Chronic stress and anxiety
• Chronic infections
The leaky gut syndrome is associated with many health problems.
Leaky gut can be evident in skin problems like eczema or psoriasis. It can be associated with heart failure, autoimmune conditions affecting the thyroid (Hashimoto’s) or joints (rheumatoid arthritis), mental illness, autism spectrum disorder, depression, and much more.
This chronic state can lead to such conditions as fibromyalgia.
Fibromyalgia sufferers experience symptoms, including:
Insomnia or difficulty sleeping
Morning stiffness
Headaches
Numbness or tingling in the hands and feet
Menstrual irregularities and pain
Difficulty concentrating (i.e. “brain fog”)
It’s the second most common musculoskeletal ailment behind arthritis, and it affects females far more often than males (it is seven times more common in women).
It is a Debilitating Condition that Affects every Aspect of Life.
People are three to four times more likely to suffer from depression.
CBD Oil and Leaky Gut Syndrome can play a Pivotal Role
Due to these similarities between CBD and our own system, some of its incredible attributes are that it has virtually no side effects and a zero percent chance of overdose. It is a huge advantage, it works very similarly to neurochemicals called endocannabinoids that are found in our own body (and that we naturally produce).
CBD Oil for Inflammation: What does Research say?
Research on CBD in animal models abounds, and the cannabinoid seems to be able to interact with the immune system, reduce inflammation, and reduce pain from several conditions. Studies date back as far as 2009, but the most recent are highlighted here.
A 2015 review published in Bioorganic and Medicinal Chemistry discussed the anti-inflammatory properties of CBD. The reviewers found that CBD reduces inflammation through several pathways in the body, and represents an effective potential treatment for a range of conditions characterized by inflammation.
A 2016 study published in Clinical Hemorheology and Microcirculation investigated CBD as a treatment for early pancreatic inflammation in diabetic mice. Pancreatic inflammation can lead to diabetes due to an invasion of immune cells that destroy insulin-producing cells. The mice who received ten weeks of treatment with CBD developed diabetes later than the mice that didn’t receive the treatment. CBD-treated mice also showed a significant reduction in immune-cell activity.
A 2017 study in the journal Pain examined the effects of CBD in male rats with osteoarthritis. After two weeks, acute inflammation of the joints was reduced by local CBD treatment applied to the area. The administration of CBD was also found to prevent the development of nerve damage and joint pain.
Research using animal models has shown that CBD may be able to modulate the immune system. While CBD does not have much affinity for the body’s cannabinoid receptors, it does affect other receptors and targets. According to a 2018 study published in Neurology, CBD binds to and desensitizes receptors known to mediate pain and sensory perception, inflammation, and body temperature.
While these results are promising, and most FDA-approved medication is initially tested on animals, rigorous clinical trials on humans are needed to move CBD from alternative treatment to approved drugs.
Conclusion
There is already a large body of scientific literature and anecdotal evidence that supports CBD Oil for Inflammation and it’s a potential treatment. It is critical to remember, however, that many of these existing studies have been animal studies, and that human trials are needed to understand more comprehensively how CBD works in humans.
it’s important to note that more research is needed to fully understand CBD’s anti-inflammatory effects and potential benefits for various human inflammatory conditions. The existing research is primarily preclinical or based on animal models, and human clinical trials are limited.
If you are considering using CBD oil for inflammation, it is advisable to consult with a healthcare professional. They can provide guidance based on your specific situation, help you understand potential risks and side effects, and ensure it doesn’t interfere with any other medications you may be taking.
Additionally, it’s crucial to choose a high-quality CBD product from a reputable source. Look for third-party lab testing to ensure the product’s purity and potency. Dosage and administration can vary depending on the individual and the targeted condition. Follow the product’s instructions or consult a healthcare professional for appropriate guidance.
Reference
https://weedmaps.com/learn/cbd/cbd-oil-inflammation
https://blisshealthcoaching.com/cbd-oil-and-gut-health-can-it-improve-leaky-gut