Many studies have been conducted on the health benefits of CBD oil and found that this compound offers individuals diagnosed with arthritis several potential benefits.
Approximately 54 million adults and 300,000 children in the U.S. diagnosed with arthritis or some other type of rheumatic disease, causing joint pain, according to the Arthritis Foundation (A.F.).
Also, the amount of undiagnosed, the A.F. suggests that the true count is likely closer to 91.2 million in total. That number is expected to grow by 49 percent by the year 2040.
The most precarious and debilitating symptoms suffered by arthritis patients include pain, stiffness, and decreased movement within the joints, all of which can be severe and worsen over time. Also, other symptoms are just as troublesome, such as anxiety and depression.
Not only that, but it can become especially trying when you have to contend with other medical problems that tend to coexist with arthritis, like heart disease, diabetes, and obesity.
Some medications and treatment programs can potentially help ease these adverse effects, but many people are searching for a more natural pain relief option. It is where the health benefits of CBD oil come into play.
Have you tried CBD for arthritis pain?
What is CBD Oil?
CBD is short for cannabidiol, which MedlinePlus explains is one of more than 80 chemical cannabinoids found in the marijuana plant Cannabis sativa. Thus, cannabis oil, or CBD oil as it is more commonly known, is an oil that is developed using this particular compound.
Although CBD oil is just now becoming reasonably mainstream, mainly because of the debates surrounding medical marijuana, cannabis has a long history of providing relief in many different countries around the world.
CBD’s Long History
In June 2015, National Geographic ran a story about how Siberian burial mounds as far back as 3000 B.C. were found to contain charred cannabis seeds. In Chinese medicine, cannabis has been used for thousands and thousands of years.
The article went on to explain how American use of cannabis goes back to our country’s founding fathers as well. George Washington himself grew hemp at his plantation estate and the location of his burial, Mount Vernon.
Because of its somewhat tumultuous history, marijuana has had with the law (regarding whether it is illegal or not), research on the favorable properties of hemp plants’ derivatives such as cannabidiol oil has been minimal.
It has caused many people to question its use for modern-day ailments, primarily because they don’t know a lot about how it works. Therefore never truly understood the health benefits of CBD oil.
How Cannabis Oil Works
According to Medical News Today, the body’s endocannabinoid system has two cannabinoid receptors: CB1 and CB2.
A majority of CB1 receptors are located in the brain and are associated with cognitive actions related to coordination, mood, thinking, memory, and appetite. The CB2 receptors, on the other hand, can be found in the immune system. It makes them more responsible for the body’s response to pain and inflammation.
Tetrahydrocannabinol, or THC, attaches to the CB1 receptors, which explains why smoking or otherwise ingesting marijuana affects users on a cognitive level.
However, CBD impacts the CB2 receptors. And it does so indirectly, not by attaching to the CB2 receptor, but by enticing the body to make more of its cannabinoids. It creates a positive effect on the body’s pain and inflammation responses.
CBD Oil Eases Arthritis Pain
One of the primary CBD oil benefits for people with arthritis is its positive effect on pain, and research confirms it.
A study published in the journal Pain in December 2017 analyzed whether CBD could prevent osteoarthritis pain and joint neuropathy. Based on their findings, researchers affirmed that it did both because it decreased joint inflammation and served as a protectant to the nerves.
CBD Oil Relieves Other Chronic Pain Conditions
CBD oil relieves other chronic pains as well. For instance, research published in Therapeutics and Clinical Risk Management indicates that cannabinoids have been helpful with easing pain for individuals diagnosed with conditions such as multiple sclerosis and cancer.
Other studies have reported positive effects for individuals taking CBD to ease their fibromyalgia pain, many of whom only experienced mild side effects from this chemical compound, such as dry mouth, drowsiness, and dizziness.
CBD Oil and Anxiety
CBD oil linked to a variety of mental health benefits, such as a reduction in anxiety. Research suggests that it is so useful in this regard that it has “considerable potential as a treatment for multiple anxiety disorders.” One study published in The Permanente Journal even found that CBD oil can help reduce anxiety in young children.
CBD Oil for Depression
Several studies have also linked CBD to a reduction of symptoms associated with depression. It is imperative because as the Arthritis Foundation says that the depression rates of those diagnosed with certain types of arthritis “can be between two- and ten-times greater than the rates of the general population.”
Is CBD Oil Legal?
Although CBD oil has several potential benefits, one of the top questions that individuals diagnosed with rheumatoid arthritis have is whether or not it is legal. Answering this question requires some understanding of the specific components of the marijuana plant.
The compound in the cannabis plant that is most well-known is THC. It is the chemical responsible for marijuana’s notorious high. However, unlike THC, CBD does not have psychoactive properties. It means that it does not create the same effect that one usually gets when smoking, inhaling, or otherwise ingesting marijuana.
Furthermore, the U.S. Drug Enforcement Administration (DEA) says that it is the THC that makes marijuana illegal in several different states.
As a result, the answer to “Is CBD oil legal?” isn’t quite so clear.
Initially, marijuana use and sales became illegal under the Marijuana Tax Act of 1937, with this illegality continuing under the Controlled Substances Act. Yet, since then, several states have taken steps to legalize this drug, even if just for use as medical cannabis.
For instance, some states allow the consumption of marijuana and its extracts only for medical reasons, which makes a medical marijuana card necessary for its use. Some states have approved this drug and its components for recreational use as well.
To make matters more complicated, on December 14, 2016, the DEA issued a Final Rule that created a new code number (7350) designed to cover “any material, compound, mixture, or preparation” surrounding the marijuana plant.
Upon clarification of this new code, the DEA indicated that CBD extracts that contain even small amounts of other cannabinoids would still fall under the old system, making them illegal under federal rule.
However, CBD extracts that contain no other cannabinoids would fall under the new code, where they could potentially be legal to use.
Plus, some CBD oils derived from hemp, the fiber of the cannabis plant. Though the 2014 Farm Bill declared particular hemp cultivation practices legal, muddying the legal waters, even more, the president signed the new Farm Bill into law in December 2018, effectively legalizing hemp under federal law.
What does all of this mean in real-life terms?
In short, to determine whether a CBD oil or any other CBD product is legal or illegal depends on a multitude of factors. Your geographical location, local laws, and whether there are any other cannabinoids in the extract must all be taken into consideration before arriving at a final answer.
Is CBD Oil Safe?
The second most common question people have when it comes to CBD oil for pain management or its anti-inflammatory properties is whether or not it is safe to use for arthritis symptoms.
Patients are always concerned with additional potential and side effects (as they should be). According to some top health experts and agencies, the answer is yes. It is safe to use.
For instance, Medscape shares that while cannabinoid medicine is still in its early stages, “unlike marijuana and THC, the risks associated with CBD are extremely low, with not a single case report of CBD overdose in the literature. The National Institute on Drug Abuse agrees and states that “CBD appears to be a safe drug with no addictive effects.”
In the future, likely, the Food and Drug Administration (FDA) will also begin to regulate CBD products, providing an additional safety net, as this agency indicates that “increasing public interest” in this substance increases the importance of establishing regulatory procedures.
Potential Risks of CBD Oil
Many health experts have deemed CBD safe to use, but like with any substance, there does appear to be a few potential risks when it comes to using this extract.
Medication/Drug Interactions
MedlinePlus indicates that CBD can sometimes interact with certain prescription medications, primarily those that are “changed and broken down by the liver.”
These include, but are not limited to conventional medications such as:
· ondansetron (Zofran)
· clozapine (Clozaril, FazaClo)
· progesterone (Endometrin, Prometrium)
· testosterone
· disulfiram (Antabuse)
· ketamine (Ketalar)
· phenobarbital (Luminal)
· omeprazole (Prilosec)
· lansoprazole (Prevacid)
· diazepam (Valium)
· carisoprodol (Soma)
· ibuprofen (Motrin)
· celecoxib (Celebrex)
· amitriptyline (Elavil)
· warfarin (Coumadin)
· codeine
· paroxetine (Paxil)
· tramadol (Ultram)
· venlafaxine (Effexor)
· alprazolam (Xanax)
· fexofenadine (Allegra)
· benzodiazepines
· morphine
MedlinePlus further states that there are other “drugs” that can potentially interact with CBD as well, including caffeine and nicotine. However, research has not necessarily supported these claims.
For instance, a 2015 study published in the journal Pharmacology Biochemistry and Behavior found that, in the right dose, caffeine can potentially help prevent CBD effects on memory.
Another piece of research, this one published in the Addictive Behaviors journal, found that CBD “significantly reduced” (as much as 40 percent) the number of cigarettes smoked by individuals who wanted to quit.
CBD and Drowsiness
Another potential risk of CBD is that it can cause drowsiness. Therefore, if you’re taking supplements or medications to help you sleep, CBD could enhance these effects even more. It’s essential to keep this in mind if you’re performing activities that require maximum alertness, such as driving or operating heavy machinery.
CBD Dosing Considerations
If you’d like to use CBD oil to help ease your arthritis pain, you may be wondering how much to administer or apply. However, when talking about proper CBD dosing, it’s vital first to understand bioavailability.
CBD Bioavailability
Defined as the “amount of a substance that becomes available to an organism’s body for bioactivity when introduced through ingestion, inhalation, injection, or skin contact.” In short, it is how much of the substance your body can effectively use based on the type and route taken.
Medscape indicates that while intranasal administration of CBD has a bioavailability of 34 to 46 percent. And CBD vaporization has 40 percent bioavailability. Oral CBD is as low as 6 percent, owing to significant first-pass metabolism.”
First-Pass Metabolism and CBD
An article published in the journal Nurse Prescribing explains that first-pass metabolism occurs in the gut or the liver and is when some of the drugs destroyed before it can circulate the body. Thus, based on the research above, taking CBD oil in pill form may mean that your body only receives as little as 6 percent of the CBD.
Another option is to take CBD oil topically, either alone or as part of a lotion or cream. Research published in the European Journal of Pain studied the effectiveness of this approach and found that “topical CBD application has therapeutic potential for relief of arthritis pain-related behaviors and inflammation without evident side-effects.”
Proper CBD Dosing
Because CBD is so new, Medscape recommends that users “start low, go slow.” It enables you to see how well your body responds without giving it more than the necessary amount.
Plus, there are no government regulations regarding the manufacture and sale of CBD, so you never know if you’re getting the amount listed on the label. It makes erring on the side of caution even more critical.
Health Benefits of CBD Oil
Consumer Health Digest (CHD) researched products on the web, and, according to this guide, the three most important terms to know before purchasing your CBD oil are CBD volume, hemp oil volume, and CBD concentration. The second and third are the most critical, according to CHD, because they indicate the oil’s potency.
It’s also important to realize that there are different product options concerning CBD oils. They are:
· CBD oil, which is the “more potent version and delivery system of CBD.”
· CBD oil topical solutions, enabling the user to use it on a more targeted area
· CBD oil tinctures, which are alcohol-based cannabis extracts that ingested orally, and the most popular CBD oil choice
· CBD dietary supplements, or capsules containing CBD oil in a powdered form
The one you choose will depend mainly on the location and severity of your pain. If you want to target a specific area, an oil or oil topical may be the best. However, if the pain is all over, then a tincture or dietary supplement may provide the most relief.
Also, if you’re new to using CBD oil, we recommend you start with 10 milligrams per day to establish a safe, adequate amount for you. Most of our R.A. colleagues end up getting relief when they take 20mg of full-spectrum lab-grade CBD tincture under the tongue twice per day. It’s essential to hold it there for at least 60 seconds. Others with more severe pain go as high as 80mg twice or more per day to get full relief.
Cannabinoids have also been found to have antioxidant properties that make it useful in the treatment in the prevention of stroke and related trauma. Cannabinoids limit neurological damage in age-related, Alzheimer’s disease, Parkinson’s disease, and dementia.
While research on CBD is ongoing, preliminary clinical research and anecdotal evidence show a strong correlation in the potential and efficacy of CBD oil. The study conducted on CBD interacts with our body and brain and to determine the health benefits of CBD oil.
